1. Punisher (Genesis)
2. Crusader of Centy (Genesis)
3. E.V.O.: The Search for Eden (SNES)
I used to REALLY want DuckTales 2, but I now have it via the Disney Afternoon Collection on Xbox 360/XBox One. Same goes for Golden Axe: Warrior (Master System), as it's an unlockable on The Sega Genesis Collection (PS2).
I've gotten a few of the ones that were on my radar already, luckily, like Mega Man Legends 2 (PS1), Bucky 'O Hare (NES), Frankenstein: The Monster Returns (NES), and Einhander (PS1). I'm sure I'm forgetting some. Many that are "holy grails" used to not be when I got them. I don't keep up on values for games I've already knocked off my wishlist.