I'd love to see a good JRPG, with the mythology and art-style of Western RPGs.
Like I want it to have the traditional experience, level-up, and menu-based battle system of a JRPG, but I want to see creatures and artwork from a Western sensibility. I want to see some bad-ass looking warriors, evil-looking mages, huge fire-breathing dragons, Elves, Orcs, Dwarves, Trolls, etc. And I want to see a Western art-style, rather than a Manga-influenced art-style.