I noticed you did not post this on SMSPower. That would be the place to ask.
While putting the famicom on there would not work due to the code being different (can't run pc games on mac). A ROM hack would theoretically be possible. Although it would be a LOT of work and may not work out perfectly. But honestly, the sonicretro community does wonders when it comes to hacking ROMs. Although, that community may not be the one to ask...
But, post this on SMSPower. Bock will probably have quick and vey knowledgable answer.