The Sega CD does have a lot of interactive movie types of games but you're probably not looking for those. All of the ones I've played have already been mentioned. Another on Sega CD is Mansion of Hidden Souls but I've never played it so I don't know how it is. Checking out a list of Genesis games it looks like maybe Beavis & Butt-Head, Scooby-Doo and Cosmic Spacehead are point and click, but again I've not played those.
