Video game going 100% digital: I wouldn't necessarily stop playing video games if this happened, but it would mean I would never buy a game upon release. The most I have ever spent on a digital game was $20 and even that was met with some regret. Essentially I wouldn't be playing new games for years after they came out, possibly into the next console generation when they'd be marked down below $10. When this happens, yes I believe it inevitably will, I will be almost exclusively a retro gamer. I believe we have one more console generation past our current gen that will embrace physical media primarily, but all bets are off after that.
Mobile gaming gains a greater presence within gaming: I don't care what anyone says, mobile gaming is a watered down, very casual form of gaming that is made soully to appeal to non-gamers. It's already a pretty popular platform and has been, but fortunately it hasn't effected console and PC gaming, mostly. I feel like many of the design decisions in Pokemon Let's Go were heavily influenced by the success of Pokemon GO, which means I have no interest in it. Likewise, Command and Conquer, one of the most iconic PC franchises has been reduced to a crappy mobile game. I really hope this trend does not continue and mobile gaming stays its own thing within infecting console gaming. I'm fairly sure, however, that this is only wishful thinking.
The DLC/micro transaction business model becomes an industry standard: This one is already sort of happening; nearly every new video game has some DLC and micro transactions are becoming more and more common as well. I suppose the silver lining to all this is that most games are not effected by the DLC if you choose not to buy it. As soon as more games start implementing pay to win schemes or progression is greatly stifled by not buying a DLC pack or the in game micro transactions then I'm out.
My outlook on the video game industry is not a positive one. Maybe it's because I'm getting older and more set in my ways, or maybe it's because I value ownership of my games (hence why I collect), but I can see all these scenarios happening within the next decade. I'm almost counting on me spending the second half of my life being only into retro games.