Earthbound: People act like it is the end all, be all RPG on the SNES, but from someone who has played most of them on the system, it is definitely bottom of the barrel, maybe mediocre at best. People like to say how unique and quarky it is, which I guess is true, especially for the time, but the graphics look slightly better than an NES game, the music is mostly not that great (with a few exceptions), and the story is pretty boring. Chrono Trigger, FFIV and FFVI, Secret of Mana, Secret of Evermore, Breath of Fire I and II, and Lufia are just a few RPGs that are better. Meanwhile, Earthbound gets treated like it's the greatest thing since sliced bread.
Honorable mentions: Metal Gear Solid, Super Smash Bros Melee, Call of Duty (all of them)