I would have to go with Dragon Ball Z: Budokai Tenkaichi 3 for the Wii. I probably have at least 500+ hours into that game and I was just amazed at the amount of playable characters, it something that the newer Dragon Ball games can't capture correctly, sadly.
A strong runner up would be Duck Tales for the Nes. Capcom is a god when it comes to making platformers and this game is no exception.