I can fairly say I collect amiibos, and I'm probably 5-6 short from a complete set w/out Cloud & Bayonetta. A year ago it was more of a hype thing, and a massive majority of fans were collecting. It was much easier trying to find amiibos on release, or waves, to which a series was produced and put on the shelves. Very early on, supply was very low and demand was very high. Some of the early series/wave amiibos were rare for quite some time, until they started to reprint some of the rarer ones as of late. I'd say if you wanted to start collecting them go for it! You can either collect the characters you like specifically, or try to go for a whole set, but keep in mind, even though the shelves are well-stocked now, you will more than probably have to go on the internet to buy the ones you are missing. I believe there are still a few pricey amiibos out there. If you have any questions let me know! I can probably help you out!
There are collectors who prefer to open their amiibos, but I keep mine in the box... don't know why lol. Just making it harder for me to display all of them... they take up ample amounts of space when you start to collect a bunch.