Of course! This is have been one of the main anxieties I've had as a collector over the past 5 or so years. That game you've been thinking about picking up for a long time, that was also kinda on the cheap side too? Well not anymore, because apparently letting it go for anything under $200 would now be ludicrous!
This is what makes game collecting so frustrating. There's no real justification for some of the "established values" that you'll come across. A game can jump from dirt cheap to super expensive, literally overnight. All it takes is one dubious precedent, like an eBay listing ending for a really inflated price. If that happens, then everyone else in possession of the game now believes they're entitled to the same money for their copy, and a license to now call it "rare". In the world of game collecting, rare just means that people will pay a lot of money for it. The majority of games out there are a lot lower in print run than your staple games / greatest hits games, already. So what is rare? 40,000 copies? 12,000? 349? Who knows. It's just whatever sellers wanna call rare.
A recent example - there is a generic racing game for GameCube called City Racer. For ages, this game sold for about $10 on eBay. Until one day, when it sold for over $100. Why? Probably because some guy bought it from himself at that price to screw with the value of it. Regardless, ever since then, it sells for big money and because of that, a number of YouTube channels have now included it in lists of "ULTRA R@RE G@meCube game$ to look out for". Even though no one gave a flip a few months back, when it was just a dirt cheap game no one wanted. That's how game collecting goes. Usually, when that happens to a game I intended to buy, I'll just give up on it. However, with Klonoa on PS1, I'll probably end up buying it because I feel like that one is not gonna stop going up. It'll crest one grand eventually and collectors will be saying "Remember when it was $300? Wish I'd jumped on it back then!"
I do think some people who buy and resell games try to watch some prominent content creators like MetalJesus and then gouge on featured items, but it doesn't always take. Regardless of who sets the ball in motion, market manipulation does go on, and it's incredibly easy to persuade collectors of the rarity and value of games they've never heard of. A lot of games became more well known for just how expensive they are, and that could potentially happen to any game at this point, I'd think.
Fortunately, I've often stayed ahead of the hidden gem in terms of ones I actually wanted to add to the collection. I feel like I have an eye for the types of games that are most susceptible to this sort of thing, and I've proven myself right many times.