Lots of great shows on RetrowareTV.com. I've found a bunch of other ones at YouTube. Here's some of my favorites that don't get discussed as much.
https://www.youtube.com/user/strafefox -- Splash Wave
This show really needs to get some attention. The production value is the best I've seen for these types of shows, even better than Game Sack. Really, go check this one out now!!!
Pushing Up Roses
She strictly reviews PC adventure games and her show is polished, fun and informative.
The Video Game Years
RetrowareTV's flagship show. Its basically VH1's "I Love The 80's" for strictly video game stuff.
wiiviewr
All well-made Wii reviews. So many Wii games are super cheap right now, it's a great time to start looking for titles that will be highly collectible in the future.
The Backlog
Nice, simple and well-made retro review show.
Lazy Game Reviews
Reviews of dusty old PC games that have long been forgotten.
The Gaming Historian
Nicely made and informative channel.
Portscenter
Reviews just ports of games to other consoles and how well the transition holds up.
And many of the other popular channels
Game Sack
Game Chasers
RetroLiberty
Gamester81
Pat the NES Punk (the podcast too, but I can't stand Ian -- he's "that guy" who comes off as condescending and he hates everything).
Metal Jesus isn't too bad. I agree with AlpahOmegaSin on nearly everything, but his videos are so laced with unnecessary profanity it makes them hard to watch (especially at work).