Team Fortress 2 - 1146 hours
Super Smash Bros. Melee -
(In the hundreds)
Castlevania: Dawn of Sorrow -
(nearly a hundred, I've been playing it for the past 9 years and have beaten it at least 6 times)
Castlevania: Harmony of Despair - 500+ (farming for Valmanway+1, Claimh Solais+1, miser rings, 10Million gold etc.)
Super Mario 64 - over 100 (funny enough I speedrun it so I put a lot of time in to put less time in per run)
Terraria - 277
Super Smash Bros. Brawl (Project M) - 100+, used to host tourneys with friends twice a month for a couple years
Final Fantasy VII - 140 over 2 runs with Knights of the Round and Final attack materia farming in the northern cave.