Ideally: Bring back additional rpg mechanics, put in meaningful dialogue and sidequest choices with interesting story lines, make siding with different factions have more of an impact, less dev time, and use a new engine
Realistically: Todd Howard will hype us up for FO5, only to end up being another ehhhhhhh game within 6 months of release.
Bethesda's internally developed products from the last few years have been dissapointing, and i don't expect much to change, especially from a management standpoint.
In a little late here, but I agree with the RPG mechanics. If we can have more meaningful dialogue and sidequests, it would be fantastic! I put countless hours into FO4, but I started to get burned out after awhile. The only thing that kept me going after awhile was the mods release.