Had a board game night yesterday. Tried the games I recently bought. Sentinels of the Multiverse is really awesome and easy to play (though I can see how it might become challenging). Say Anything is a blast. No one liked Wits and Wagers (partly because one of the people playing just hated it for no reason, and Say Anything is just a lot better). King of Tokyo was fun, but it's really not a 6-player game.
Finally, a friend brought over Quarriors, which he borrowed from his sister, and it kicked ass. Out of all the games we played, Quarriors and Sentinels of the Multiverse were definitely the best, I highly recommend both.